N-(4-Chloro-3-(trifluoromethyl)phenyl)-6-nitroquinazolin-4-amine

The molecule incorporates a quinazoline heterocyclic core, a nitro group, and a chlorotrifluoromethyl-substituted phenyl moiety, structural features often utilized in the development of kinase inhibitors and other targeted therapeutic agents. It serves as a key building block in pharmaceutical research, process development, and the manufacture of active pharmaceutical ingredient (API) intermediates. N-(4-Chloro-3-(trifluoromethyl)phenyl)-6-nitroquinazolin-4-amine is a quinazoline-based pharmaceutical intermediate used in medicinal chemistry and the synthesis of biologically active compounds.

API Name Dacomitinib
CAS No 1290545-23-1
Molecular Formula C15H8ClF3N4O2
Molecular Weight 368.70 g/mol
Synonyms N-[4-chloro-3-(trifluoromethyl)phenyl]-6-nitroquinazolin-4-amine

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