Morphine-6-glucuronide (M6G) is a potent metabolite of morphine that functions as a strong µ-opioid receptor agonist, contributing to the analgesic (pain-relieving) effects of morphine. While it can be administered parenterally and intrathecally, its primary role is as an active metabolite contributing to the overall analgesic effect of morphine, potentially with reduced side effects. Its therapeutic use is listed as analgesics. The directory classifies it as a clinical API with a semi-synthetic source/manufacturing origin. Other names for this substance include glucuronido de morfina and morphini glucuronidum. Its PubChem CID is 5360621.
Morphine 6-glucuronide
| CAS No | 20290-10-2 |
|---|---|
| Molecular Formula | C23H27NO9 |
| Molecular Weight | 461.50 g/mol |
| Synonyms | (2S,3S,4S,5R,6R)-6-[[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid |
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Frequently Asked Questions
Morphine-6-glucuronide (M6G) is a potent metabolite of morphine that functions as a strong µ-opioid receptor agonist, contributing to the analgesic (pain-relieving) effects of morphine.
The listed CAS number is 20290-10-2.
The listed molecular formula is C23H27NO9.
The listed molecular weight is 461.50 g/mol.
(2S,3S,4S,5R,6R)-6-[[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.
The source lists glucuronido de morfina and morphini glucuronidum.