Monomethyl fumarate is a dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1. Among its listed roles, it functions as a immunomodulator, an antioxidant and a drug metabolite. It is an enoate ester, a methyl ester and a dicarboxylic acid monoester. Functionally, it is related to fumaric acid. It is grouped under the following drug class(es): Immunosuppressants. Its therapeutic use is listed as multiple sclerosis agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Bafiertam and Fumaric acid monomethyl ester. Its PubChem CID is 5369209.
Monomethyl fumarate
| CAS No | 44836-34-2 |
|---|---|
| Molecular Formula | C5H6O4 |
| Molecular Weight | 130.10 g/mol |
| Synonyms | (E)-4-methoxy-4-oxobut-2-enoic acid |
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Frequently Asked Questions
Monomethyl fumarate is a dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS).
The listed CAS number is 44836-34-2.
The listed molecular formula is C5H6O4.
The listed molecular weight is 130.10 g/mol.
(E)-4-methoxy-4-oxobut-2-enoic acid.
The source lists Bafiertam and Fumaric acid monomethyl ester.