Mithramycin is a carbohydrate-containing antibiotic, an anthracycline antibiotic, an aureolic acid and a secondary alpha-hydroxy ketone. Among its listed roles, it functions as a antineoplastic agent, an EC 2.7.7.6 (RNA polymerase) inhibitor and a metabolite. It is grouped under the following drug class(es): Cytotoxics. The directory classifies it as a discontinued API with a fermentation-derived source/manufacturing origin. Other names for this substance include plicamycin and Aureolic acid. Its PubChem CID is 163659.
Mithramycin
| CAS No | 18378-89-7 |
|---|---|
| Molecular Formula | C52H76O24 |
| Molecular Weight | 1085.10 g/mol |
| Synonyms | (2S,3S)-2-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4-[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-6-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-8,9-dihydroxy-7-methyl-3,4-dihydro-2H-anthracen-1-one |
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Frequently Asked Questions
Mithramycin is a carbohydrate-containing antibiotic, an anthracycline antibiotic, an aureolic acid and a secondary alpha-hydroxy ketone. 6 (RNA polymerase) inhibitor and a metabolite.
The listed CAS number is 18378-89-7.
The listed molecular formula is C52H76O24.
The listed molecular weight is 1085.10 g/mol.
(2S,3S)-2-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4-[(2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-6-[(2S,4R,5R,6R)-4-[(2S,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-8,9-dihydroxy-7-methyl-3,4-dihydro-2H-anthracen-1-one.
The source lists plicamycin and Aureolic acid.