Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing syndrome. The two marketed forms of mifepristone are Mifeprex® (mifepristone 200mg) and Korlym™ (mifepristone 300mg). Currently under investigation for use in psychotic depression. Its therapeutic use is listed as alcohol dependence agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Mifegyne, Mifeprex, Korlym and Pictovir. Its PubChem CID is 55245.
Mifepristone
| CAS No | 84371-65-3 |
|---|---|
| Molecular Formula | C29H35NO2 |
| Molecular Weight | 429.60 g/mol |
| Synonyms | (8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one |
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Frequently Asked Questions
Mifepristone is a progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua.
The listed CAS number is 84371-65-3.
The listed molecular formula is C29H35NO2.
The listed molecular weight is 429.60 g/mol.
(8S,11R,13S,14S,17S)-11-[4-(dimethylamino)phenyl]-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one.
The source lists Mifegyne, Mifeprex, Korlym and Pictovir.