Metolazone

Metolazone is a quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics. Among its listed roles, it functions as a diuretic, an antihypertensive agent and an ion transport inhibitor. It belongs to the class of quinazolines, an organochlorine compound and a sulfonamide. It is grouped under the following drug class(es): Diuretics. Its therapeutic use is listed as antihypertensives and cardiovascular. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Zaroxolyn, Diulo, Mykrox and Xuret. Its PubChem CID is 4170.