Methyl 8-chloro-6-hydroxyoctanoate

Its key function is as a building block in complex organic syntheses, often produced via stereoselective biocatalysis (like ketoreductases) for purity. Methyl 8-chloro-6-hydroxyoctanoate is used mainly as a crucial intermediate in the synthesis of α-lipoic acid, particularly the biologically active (R)-enantiomer, for pharmaceutical (diabetic neuropathy) and supplement uses, as well as a reference standard for analytical testing (QC/method validation) in drug development, especially for related impurities.

API Name Alpha lipoic acid
CAS No 75033-15-7
Molecular Formula C9H17ClO3
Molecular Weight 208.68 g/mol
Synonyms methyl 8-chloro-6-hydroxyoctanoate