Methyl 4-fluoro-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzoate

The compound itself is not a final drug but a crucial building block in the manufacturing process of the active pharmaceutical ingredient (API). Methyl 4-fluoro-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzoate is a pharmaceutical intermediate employed to synthesize Venetoclax (ABT 199), a BCL-2 inhibitor that is used to treat certain cancers, such as chronic lymphocytic leukemia and estrogen receptor-positive breast cancer.

API Name Venetoclax
CAS No 1235865-75-4
Molecular Formula C15H11FN2O3
Molecular Weight 286.26 g/mol
Synonyms methyl 4-fluoro-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate