methacetin-(methoxy-(13)C)

Methacetin-(methoxy-(13)C) is a (13)C-modified compound that is methacetin which has (13)C as the predominant isotope of the methoxy carbon. In normal subjects, methacetin is rapidly metabolised in the liver, being dealkylated by hepatic CYP1A2 to give paracetamol (acetaminophen); the methyl of the methoxy group is eliminated as CO2. Administering methacetin-(methoxy-(13)C) to a patient enables the liver (cytochrome P-450 1A2) function to be determined quickly and precisely by measuring the (13)CO2 in the breath (e.g. by isotope-selective non-dispersive infrared spectrometry (NDIRS)). Among its listed roles, it functions as a isotopic tracer and a diagnostic agent. It is a (13)C-modified compound, a member of acetamides and an aromatic ether. The directory classifies it as a unknown/inactive API with a synthetic source/manufacturing origin. Other names for this substance include p-Acetanisidine C-13, Acetamide, N-(4-(methoxy-13C)phenyl)-, (13)C-methacetin and N-(4-(Methoxy-13C)phenyl)acetamide. Its PubChem CID is 9793926.