Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America. It has been found to have carcinogenic potential in mammalian cells as well as cytotoxic properties. Studies involving the active metabolite of this formulation, menadione, showed oocyte toxicity in a study of mice. Its therapeutic use is listed as hematologic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Synkavit and Kappadione. Its PubChem CID is 8555.
Menadiol sodium diphosphate
| CAS No | 131-13-5 |
|---|---|
| Molecular Formula | C11H8Na4O8P2 |
| Molecular Weight | 422.08 g/mol |
| Synonyms | tetrasodium;(2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate |
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Frequently Asked Questions
Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America.
The listed CAS number is 131-13-5.
The listed molecular formula is C11H8Na4O8P2.
The listed molecular weight is 422.08 g/mol.
tetrasodium;(2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate.
The source lists Synkavit and Kappadione.