Memantine

Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. Among its listed roles, it functions as a dopaminergic agent, an antiparkinson drug, a NMDA receptor antagonist, a neuroprotective agent and an antidepressant. It belongs to the class of adamantanes and a primary aliphatic amine. It is the conjugate base of memantinium(1+). It is derived from a hydride of an adamantane. It is grouped under the following drug class(es): Psychotropic agents. Its therapeutic use is listed as central nervous system (CNS) agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include nemdatine, Axura, Namenda, 1-Amino-3 and 5-dimethyladamantane. Its PubChem CID is 4054.