Memantine hydrochloride

Memantine hydrochloride is a hydrochloride obtained by reaction of memantine with one equivalent of hydrochloric acid. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. Among its listed roles, it functions as a antidepressant, an antiparkinson drug, a dopaminergic agent, a neuroprotective agent and a NMDA receptor antagonist. It includes a memantinium. It is grouped under the following drug class(es): Neurotransmitter agents. Its therapeutic use is listed as alcohol dependence agents and central nervous system (CNS) agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Akatinol, Namenda XR, Memary and Memantine Mylan. Its PubChem CID is 181458.

CAS No 41100-52-1
Molecular Formula C12H22ClN
Molecular Weight 215.76 g/mol
Synonyms 3,5-dimethyladamantan-1-amine;hydrochloride

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