It functions by binding to tubulin to disrupt cell division, inducing apoptosis in cancer cells. With a potency 100-1,000 times greater than standard chemotherapy, it serves as the critical chemical building block for “warheads” like DM1 (mertansine). It is used strictly for research and manufacturing and is not for direct clinical use. Maytansinol-N-methyl-L-alanyl ester is a potent synthetic microtubule inhibitor and a primary payload intermediate for Antibody-Drug Conjugates (ADCs).
Maytansinol-N-methyl-L-alanyl ester
| CAS No | 77668-69-0 |
|---|---|
| Molecular Formula | C32H44ClN3O9 |
| Molecular Weight | 650.2 g/mol |
| Synonyms | [(1S,5S,6S,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0 -Show More |
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