Maytansinol-N-methyl-L-alanyl ester

It functions by binding to tubulin to disrupt cell division, inducing apoptosis in cancer cells. With a potency 100-1,000 times greater than standard chemotherapy, it serves as the critical chemical building block for “warheads” like DM1 (mertansine). It is used strictly for research and manufacturing and is not for direct clinical use. Maytansinol-N-methyl-L-alanyl ester is a potent synthetic microtubule inhibitor and a primary payload intermediate for Antibody-Drug Conjugates (ADCs).

CAS No 77668-69-0
Molecular Formula C32H44ClN3O9
Molecular Weight 650.2 g/mol
Synonyms [(1S,5S,6S,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0 -Show More