It functions by binding to tubulin to disrupt cell division, inducing apoptosis in cancer cells. With a potency 100-1,000 times greater than standard chemotherapy, it serves as the critical chemical building block for “warheads” like DM1 (mertansine). It is used strictly for research and manufacturing and is not for direct clinical use. Maytansinol-N-methyl-L-alanyl ester is a potent synthetic microtubule inhibitor and a primary payload intermediate for Antibody-Drug Conjugates (ADCs).
Maytansinol-N-methyl-L-alanyl ester
| CAS No | 77668-69-0 |
|---|---|
| Molecular Formula | C32H44ClN3O9 |
| Molecular Weight | 650.2 g/mol |
| Synonyms | [(1S,5S,6S,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0 -Show More |
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It functions by binding to tubulin to disrupt cell division, inducing apoptosis in cancer cells. With a potency 100-1,000 times greater than standard chemotherapy, it serves as the critical chemical building block for "warheads" like DM1 (mertansine). It is used strictly for research and manufacturing and is not for direct clinical use. Maytansinol-N-methyl-L-alanyl ester is a potent synthetic microtubule inhibitor and a primary payload intermediate for Antibody-Drug Conjugates (ADCs).
The CAS number of Maytansinol-N-methyl-L-alanyl ester is 77668-69-0.
The molecular formula of Maytansinol-N-methyl-L-alanyl ester is C32H44ClN3O9.
The listed molecular weight of Maytansinol-N-methyl-L-alanyl ester is 650.2 g/mol.
The listed synonym or IUPAC name for Maytansinol-N-methyl-L-alanyl ester is [(1S,5S,6S,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.0 -Show More.