Masoprocol

Masoprocol is the meso-form of nordihydroguaiaretic acid. An antioxidant found in the creosote bush, Larrea divaricata, it is a potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. It also inhibits (though to a lesser extent) formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase. Among its listed roles, it functions as a antineoplastic agent, a lipoxygenase inhibitor, a hypoglycemic agent and a metabolite. The directory classifies it as a discontinued API with a natural source/manufacturing origin. Other names for this substance include Actinex and meso-Nordihydroguaiaretic acid. Its PubChem CID is 71398.

CAS No 27686-84-6
Molecular Formula C18H22O4
Molecular Weight 302.40 g/mol
Synonyms 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol

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