Mafenide

Mafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. In 1998, mafenide acetate was approved under the FDA’s accelerated approval regulations. In November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Ambamide, Homosulfanilamide, Maphenid and Septicid. Its PubChem CID is 3998.