Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction. Lisinopril and [captopril] are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system. ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Lisinopril was granted FDA approval on 29 December 1987. It is grouped under the following drug class(es): ACE Inhibitors. Its therapeutic use is listed as antihypertensives, cardiovascular and migraine preventive agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Prinivil, Zestril and Lisinopril anhydrous. Its PubChem CID is 5362119.
Lisinopril
| CAS No | 76547-98-3 |
|---|---|
| Molecular Formula | C21H31N3O5 |
| Molecular Weight | 405.50 g/mol |
| Synonyms | (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid |
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Frequently Asked Questions
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction. Lisinopril and [captopril] are the only ACEIs that are not prodrugs.
The listed CAS number is 76547-98-3.
The listed molecular formula is C21H31N3O5.
The listed molecular weight is 405.50 g/mol.
(2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid.
The source lists Prinivil, Zestril and Lisinopril anhydrous.