Lidocaine hydrochloride

Lidocaine Hydrochloride is the hydrochloride salt form of lidocaine, an aminoethylamide and a prototypical member of the amide class anesthetics. Lidocaine interacts with voltage-gated Na+ channels in the nerve cell membrane and blocks the transient increase in permeability of excitable membranes to Na+. This prevents the generation and conduction of nerve impulses and produces a reversible loss of sensation. Lidocaine hydrochloride also exhibits class IB antiarrhythmic effects. The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability. It is grouped under the following drug class(es): Amide local anesthetics. Its therapeutic use is listed as anesthetics, cardiovascular, dermatologicals and sexual dysfunction agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Xylocaine Viscous, Anestacon, Lidocaton and Glydo. Its PubChem CID is 6314.