Levonordefrin is the levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin’s antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Corbadrine, Neo-Cobefrin and Corbadrina. Its PubChem CID is 164739.
Levonordefrin
| CAS No | 829-74-3 |
|---|---|
| Molecular Formula | C9H13NO3 |
| Molecular Weight | 183.20 g/mol |
| Synonyms | 4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol |
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Levonordefrin is the levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects.
The listed CAS number is 829-74-3.
The listed molecular formula is C9H13NO3.
The listed molecular weight is 183.20 g/mol.
4-[(1R,2S)-2-amino-1-hydroxypropyl]benzene-1,2-diol.
The source lists Corbadrine, Neo-Cobefrin and Corbadrina.