Levoleucovorin calcium pentahydrate

Calcium levofolinate is used to reduce harmful effects of methotrexate chemotherapy. It functions as a folate derivative that bypasses the blocked folic acid pathway. The active metabolite of Folic acid, Pteroyl-D-glutamic acid is used principally as its calcium salt as an antidote to folic acid antagonists which block the conversion of folic acid to folinic acid. Folic acid, a water-soluble B-complex vitamin, is found in foods including liver, kidneys, yeast, and leafy, green vegetables. Folic acid is used to diagnose folate deficiency and to treat topical sprue and megaloblastic and macrocytic anemias, hematologic complications resulting from a deficiency in folic acid. A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Fusilev, Calcium Levofolinate Pentahydrate and Isovorin (TN). Its PubChem CID is 135465090.