Ivacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol. Used for the treatment of cystic fibrosis. Among its listed roles, it functions as a CFTR potentiator and an orphan drug. It is a quinolone, a member of phenols, an aromatic amide and a monocarboxylic acid amide. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include VX-770, Kalydeco, CHEBI:66901 and 1Y740ILL1Z. Its PubChem CID is 16220172.
Ivacaftor
| CAS No | 873054-44-5 |
|---|---|
| Molecular Formula | C24H28N2O3 |
| Molecular Weight | 392.5 g/mol |
| Synonyms | N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide |
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Frequently Asked Questions
Ivacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid with the amino group of 5-amino-2,4-di-tert-butylphenol.
The listed CAS number is 873054-44-5.
The listed molecular formula is C24H28N2O3.
The listed molecular weight is 392.5 g/mol.
N-(2,4-ditert-butyl-5-hydroxyphenyl)-4-oxo-1H-quinoline-3-carboxamide.
The source lists VX-770, Kalydeco, CHEBI:66901 and 1Y740ILL1Z.