Ipamorelin

Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone. It is grouped under the following drug class(es): Compounded peptides and Peptides. Its therapeutic use is listed as compounding pharmacy peptides. The directory classifies it as a under development API with a peptide source/manufacturing origin. Other names for this substance include Aib-His-D-2-Nal-D-Phe-Lys-NH2. Its PubChem CID is 9831659.

CAS No 170851-70-4
Molecular Formula C38H49N9O5
Molecular Weight 711.9 g/mol
Synonyms (2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide

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