Iobenguane I-123 is an iodine (I) 123 labeled aralkylguanidine norepinephrine analogue used as a diagnostic imaging tracer. Iobenguane, structurally related to norepinephrine, functioning as a false substrate of norepinephrine, and is taken up and localized in the granules of pre-synaptic adrenergic neurons. When labeled with I-123, this agent is useful for the imaging of neuroendocrine tissues and tumors. Its therapeutic use is listed as diagnostic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Andreview and (123)I-MIBG. Its PubChem CID is 135326.
Iobenguane I-123
| CAS No | 76924-93-1 |
|---|---|
| Molecular Formula | C8H10IN3 |
| Molecular Weight | 271.09 g/mol |
| Synonyms | 2-[(3-(123I)iodophenyl)methyl]guanidine |
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Iobenguane I-123 is an iodine (I) 123 labeled aralkylguanidine norepinephrine analogue used as a diagnostic imaging tracer. Iobenguane, structurally related to norepinephrine, functioning as a false substrate of norepinephrine, and is taken up and localized in the granules of pre-synaptic adrenergic neurons.
The listed CAS number is 76924-93-1.
The listed molecular formula is C8H10IN3.
The listed molecular weight is 271.09 g/mol.
2-[(3-(123I)iodophenyl)methyl]guanidine.
The source lists Andreview and (123)I-MIBG.