Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, that is often aberrated in cancers including cholangiocarcinoma, infigratinib suppresses tumour growth. Cholangiocarcinoma is the most common primary malignancy affecting the biliary tract and the second most common primary hepatic malignancy. It is grouped under the following drug class(es): Kinase inhibitors and Tyrosine Kinase Inhibitors. Its therapeutic use is listed as anti-cancer agents. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Infigratinib and infigratinibum. Its PubChem CID is 53235510.
Infigratinib
| CAS No | 872511-34-7 |
|---|---|
| Molecular Formula | C26H31Cl2N7O3 |
| Molecular Weight | 560.5 g/mol |
| Synonyms | 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-[6-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]-1-methylurea |
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Frequently Asked Questions
Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, that is often aberrated in cancers including cholangiocarcinoma, infigratinib suppresses tumour growth.
The listed CAS number is 872511-34-7.
The listed molecular formula is C26H31Cl2N7O3.
The listed molecular weight is 560.5 g/mol.
3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-[6-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]-1-methylurea.
The source lists Infigratinib and infigratinibum.