Indomethacin sodium

Indomethacin Sodium is the sodium salt of indomethacin, a methylated indole derivative with anti-inflammatory, analgesic-antipyretic and tocolytic effects. Indomethacin is a non-selective, reversible, and competitive inhibitor of cyclooxygenases 1 and 2, thereby blocking the conversion of arachidonic acid into prostaglandin precursors. Consequently, prostaglandin synthesis is decreased, and prostaglandin-mediated activities are prevented, including pain, inflammation, fever and uterine contraction. It is grouped under the following drug class(es): Non-Steroidal Anti-Inflammatory Drugs (NSAID). Its therapeutic use is listed as anti-inflammatories, antirheumatic agents and osteoarthritis agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Indocin I.V. and Indomethacin sodium trihydrate. Its PubChem CID is 23675763.

CAS No 7681-54-1
Molecular Formula C19H15ClNNaO4
Molecular Weight 379.8 g/mol
Synonyms sodium;2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate

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