Indocyanine Green is a nontoxic, fluorescent, tricarbocyanine dye with a peak spectral absorption at 790 nm, with application in determining cardiac output, hepatic function, liver blood flow, as well as ophthalmic angiography. Upon administration, indocyanine green (ICG) rapidly binds to its principle carrier, plasma protein, and is thereby confined to the vascular space. This agent, with a half-life of 150 to 180 seconds, is removed exclusively by the liver from circulation to bile juice. Furthermore, due to poor uptake, ICG is not suitable for angiography or functional output analysis of kidney, lung, cerebro-spinal, or peripheral tissues. Its therapeutic use is listed as diagnostic agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Wofaverdin, Cardiogreen and Ujoviridin. Its PubChem CID is 5282412.
Indocyanine green
| CAS No | 3599-32-4 |
|---|---|
| Molecular Formula | C43H47N2NaO6S2 |
| Molecular Weight | 775.0 g/mol |
| Synonyms | sodium;4-[(2Z)-2-[(2E,4E,6E)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate |
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Frequently Asked Questions
Indocyanine Green is a nontoxic, fluorescent, tricarbocyanine dye with a peak spectral absorption at 790 nm, with application in determining cardiac output, hepatic function, liver blood flow, as well as ophthalmic angiography.
The listed CAS number is 3599-32-4.
The listed molecular formula is C43H47N2NaO6S2.
The listed molecular weight is 775.0 g/mol.
sodium;4-[(2Z)-2-[(2E,4E,6E)-7-[1,1-dimethyl-3-(4-sulfonatobutyl)benzo[e]indol-3-ium-2-yl]hepta-2,4,6-trienylidene]-1,1-dimethylbenzo[e]indol-3-yl]butane-1-sulfonate.
The source lists Wofaverdin, Cardiogreen and Ujoviridin.