Indicine N-oxide is a pyrrolizidine alkaloid with a history of research and clinical trials for its potential anti-cancer properties. It has shown antitumour and antimitotic activity in preclinical and clinical studies, particularly against certain types of leukemia and solid tumors. However, its use in humans has been limited due to concerns about toxicity, specifically liver damage and bone marrow suppression. The directory classifies it as a discontinued API with a natural source/manufacturing origin. Other names for this substance include Indicine and N-oxide. Its PubChem CID is 46854571.
Indicine-n-oxide
| CAS No | 41708-76-3 |
|---|---|
| Molecular Formula | C15H25NO6 |
| Molecular Weight | 315.36 g/mol |
| Synonyms | [(7R,8S)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2-hydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoate |
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Indicine N-oxide is a pyrrolizidine alkaloid with a history of research and clinical trials for its potential anti-cancer properties. It has shown antitumour and antimitotic activity in preclinical and clinical studies, particularly against certain types of leukemia and solid tumors.
The listed CAS number is 41708-76-3.
The listed molecular formula is C15H25NO6.
The listed molecular weight is 315.36 g/mol.
[(7R,8S)-7-hydroxy-4-oxido-5,6,7,8-tetrahydro-3H-pyrrolizin-4-ium-1-yl]methyl (2R)-2-hydroxy-2-[(1S)-1-hydroxyethyl]-3-methylbutanoate.
The source lists Indicine and N-oxide.