Iloprost is a carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension. Among its listed roles, it functions as a platelet aggregation inhibitor and a vasodilator agent. It is a monocarboxylic acid, a secondary alcohol and a carbobicyclic compound. It is grouped under the following drug class(es): Antiplatelets, Antithrombotic agents, Prostaglandins and Vasodilating agents. Its therapeutic use is listed as cardiovascular. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Ventavis, Ilomedin, Aurlumyn and Endoprost. Its PubChem CID is 5311181.
Iloprost
| CAS No | 78919-13-8 |
|---|---|
| Molecular Formula | C22H32O4 |
| Molecular Weight | 360.47 g/mol |
| Synonyms | (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid |
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Iloprost is a carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group.
The listed CAS number is 78919-13-8.
The listed molecular formula is C22H32O4.
The listed molecular weight is 360.47 g/mol.
(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid.
The source lists Ventavis, Ilomedin, Aurlumyn and Endoprost.