Icotrokinra hydrochloride is an investigational/approved IL-23 receptor (IL-23R) antagonist used mainly for the treatment of moderate-to-severe plaque psoriasis. It is the hydrochloride salt form of icotrokinra (also known as JNJ-2113 / JNJ-77242113). It is grouped under the following drug class(es): Interleukin Inhibitors. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include JNJ-77242113 hydrochloride, pyridinyl)-L-alanyl-N2-methyl-, cyclic (1–>6)-disulfide and hydrochloride (1:1). Its PubChem CID is 171390009.
Icotrokinra hydrochloride
| CAS No | 2763602-17-9 |
|---|---|
| Molecular Formula | C90H121ClN20O22S2 |
| Molecular Weight | 1934.6 g/mol |
| Synonyms | (4S)-4-[[4-[[(2S)-2-[[(2S)-2-[[(4R,7S,10S,13S,16S,19R)-19-acetamido-7-(4-acetamidobutyl)-16-(2-amino-2-oxoethyl)-13-[(1R)-1-hydroxyethyl]-3,3,20,20-tetramethyl-10-[(7-methyl-1H-indol-3-yl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]amino]-3-[4-(2-aminoethoxy)phenyl]propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]oxane-4-carbonyl]amino]-5-[[(2S)-4-amino-1-[[(2S)-1-[(2-amino-2-oxoethyl)-methylamino]-1-oxo-3-pyridin-3-ylpropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-oxopentanoic acid;hydrochloride |
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Frequently Asked Questions
Icotrokinra hydrochloride is an investigational/approved IL-23 receptor (IL-23R) antagonist used mainly for the treatment of moderate-to-severe plaque psoriasis.
The listed CAS number is 2763602-17-9.
The listed molecular formula is C90H121ClN20O22S2.
The listed molecular weight is 1934.6 g/mol.
The source lists JNJ-77242113 hydrochloride, pyridinyl)-L-alanyl-N2-methyl-, cyclic (1-->6)-disulfide and hydrochloride (1:1).
It is listed under Interleukin Inhibitors.