Guanfacine hydrochloride

Guanfacine Hydrochloride is the hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05). It is grouped under the following drug class(es): Alpha-2 agonists. Its therapeutic use is listed as ADHD agents, cardiovascular and migraine preventive agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Intuniv, Hydrochloride and Guanfacine. Its PubChem CID is 71401.

CAS No 29110-48-3
Molecular Formula C9H10Cl3N3O
Molecular Weight 282.5 g/mol
Synonyms N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride

Frequently Asked Questions