Genaconazole is a triazole-class antifungal agent developed mainly for research use. It inhibits ergosterol synthesis in fungal cell membranes, making it effective against fungal infections including cryptococcal meningitis in HIV patients. It also serves as a pharmacological model in antifungal research. Its therapeutic use is listed as antifungals. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include (2R, 3R)-2-(2, 4-difluorophenyl)-3-methylsulfonyl-1-(1, 2, 4-triazol-1-yl)butan-2-ol, (R, R)1-[1-(Methylsulfonyl)ethyl]-1-[1- triazolomethyl]-2 and 4-difluorophenylmethanol. Its PubChem CID is 452261.
Genaconazole
| CAS No | 120924-80-3 |
|---|---|
| Molecular Formula | C13H15F2N3O3S |
| Molecular Weight | 331.34 g/mol |
| Synonyms | (2R,3R)-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1,2,4-triazol-1-yl)butan-2-ol |
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Frequently Asked Questions
Genaconazole is a triazole-class antifungal agent developed mainly for research use. It inhibits ergosterol synthesis in fungal cell membranes, making it effective against fungal infections including cryptococcal meningitis in HIV patients.
The listed CAS number is 120924-80-3.
The listed molecular formula is C13H15F2N3O3S.
The listed molecular weight is 331.34 g/mol.
(2R,3R)-2-(2,4-difluorophenyl)-3-methylsulfonyl-1-(1,2,4-triazol-1-yl)butan-2-ol.
The source lists (2R, 3R)-2-(2, 4-difluorophenyl)-3-methylsulfonyl-1-(1, 2, 4-triazol-1-yl)butan-2-ol, (R, R)1-[1-(Methylsulfonyl)ethyl]-1-[1- triazolomethyl]-2 and 4-difluorophenylmethanol.