Fosfomycin Tromethamine is the tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase. This leads to an irreversible blockage of the condensation of uridine diphosphate-N-acetylglucosamine with p-enolpyruvate, that is one of the first steps of bacterial cell wall synthesis, thereby eventually causing cell lysis. Additionally, fosfomycin tromethamine reduces the adherence of bacteria to uroepithelial cells. The directory classifies it as a commercial API with a fermentation-derived source/manufacturing origin. Other names for this substance include Monurol and Monuril. Its PubChem CID is 10199068.
Fosfomycin tromethamine
| CAS No | 78964-85-9 |
|---|---|
| Molecular Formula | C7H18NO7P |
| Molecular Weight | 259.19 g/mol |
| Synonyms | 2-amino-2-(hydroxymethyl)propane-1,3-diol;[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid |
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Fosfomycin Tromethamine is the tromethamine salt form of fosfomycin, a synthetic broad-spectrum antibiotic. Fosfomycin tromethamine binds to and inactivates the enzyme enolpyruvyl transferase.
The listed CAS number is 78964-85-9.
The listed molecular formula is C7H18NO7P.
The listed molecular weight is 259.19 g/mol.
2-amino-2-(hydroxymethyl)propane-1,3-diol;[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid.
The source lists Monurol and Monuril.