Fosaprepitant is a morpholine derivative that is the (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl ether of (3-{[(2R,3S)-3-(4-fluorophenyl)-2-hydroxymorpholin-4-yl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid. Among its listed roles, it functions as a antiemetic, a neurokinin-1 receptor antagonist and a prodrug. It belongs to the class of morpholines, a member of triazoles, a cyclic acetal, a phosphoramide and a member of (trifluoromethyl)benzenes. It is the conjugate acid of fosaprepitant. Its therapeutic use is listed as gastrointestinal agents. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include fosaprepitantum and Aprepitant impurity 47. Its PubChem CID is 135413538.
Fosaprepitant
| CAS No | 172673-20-0 |
|---|---|
| Molecular Formula | C23H22F7N4O6P |
| Molecular Weight | 614.40 g/mol |
| Synonyms | [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid |
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Frequently Asked Questions
Fosaprepitant is a morpholine derivative that is the (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl ether of (3-{[(2R,3S)-3-(4-fluorophenyl)-2-hydroxymorpholin-4-yl]methyl}-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid.
The listed CAS number is 172673-20-0.
The listed molecular formula is C23H22F7N4O6P.
The listed molecular weight is 614.40 g/mol.
[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid.
The source lists fosaprepitantum and Aprepitant impurity 47.