Fmoc-leucine is mainly used as a key building block in solid-phase peptide synthesis (SPPS), where the Fmoc group protects the amino-terminus of the amino acid leucine during the formation of peptides. It is also employed in the synthesis of biomaterials and as a component in biomedical research, particularly for developing peptide-based therapeutic drugs and studying protein structures. While it has other uses as a PPARγ modulator, its main application is within the realm of peptide synthesis and drug development. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include N-Fmoc leucine and Fmoc-Leu-OH. It is also listed for alternate use as: API Intermediate. Its PubChem CID is 1549133.
Fmoc-leucine
| CAS No | 35661-60-0 |
|---|---|
| Molecular Formula | C21H23NO4 |
| Molecular Weight | 353.40 g/mol |
| Synonyms | (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid |
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Frequently Asked Questions
Fmoc-leucine is mainly used as a key building block in solid-phase peptide synthesis (SPPS), where the Fmoc group protects the amino-terminus of the amino acid leucine during the formation of peptides.
The listed CAS number is 35661-60-0.
The listed molecular formula is C21H23NO4.
The listed molecular weight is 353.40 g/mol.
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid.
The source lists N-Fmoc leucine and Fmoc-Leu-OH.