FK1706 is a non-immunosuppressive FKBP (immunophilin) ligand that promotes neuroregeneration—including neurite outgrowth, nerve repair in diabetic neuropathy, bladder function recovery, and erectile function—in multiple rat models via FKBP-52/Ras/Raf/MAPK/ERK signaling . The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include OP5, FK-1706 and FK1706. Its PubChem CID is 9811140.
FK 1706
| CAS No | 124554-37-6 |
|---|---|
| Molecular Formula | C44H69NO13 |
| Molecular Weight | 820.0 g/mol |
| Synonyms | (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone |
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FK1706 is a non-immunosuppressive FKBP (immunophilin) ligand that promotes neuroregeneration—including neurite outgrowth, nerve repair in diabetic neuropathy, bladder function recovery, and erectile function—in multiple rat models via FKBP-52/Ras/Raf/MAPK/ERK signaling .
The listed CAS number is 124554-37-6.
The listed molecular formula is C44H69NO13.
The listed molecular weight is 820.0 g/mol.
(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(2-oxopropyl)-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone.
The source lists OP5, FK-1706 and FK1706.