Fexinidazole

Fexinidazole is a nitroimidazole antimicrobial agent used to treat African trypanosomiasis, a severe and usually fatal parasitic infection caused by Trypanosoma brucei gambiense, also known as sleeping sickness. Fexinidazole is commonly associated with serum aminotransferase elevations when given in high doses for more than a few weeks, but elevations are uncommon and generally mild and transient when fexinidazole is given in the recommended doses for 10 days for African trypanosomiasis. It is grouped under the following drug class(es): QTc-prolonging agents and Trypanosomiasis agents. Its therapeutic use is listed as anti-infectives, antiparasitics and antiprotozoals. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Fexinidazol and Fexinidazolum. Its PubChem CID is 68792.