Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types. This agent also inhibits tumor growth by modulating angiogenesis-associated growth factors and their receptors and exhibits retinoid receptor-independent apoptotic properties. It is grouped under the following drug class(es): Retinoids. The directory classifies it as a under development API with a synthetic source/manufacturing origin. Other names for this substance include Fenretinidum and Fenretinimide. Its PubChem CID is 5288209.
Fenretinide
| CAS No | 65646-68-6 |
|---|---|
| Molecular Formula | C26H33NO2 |
| Molecular Weight | 391.50 g/mol |
| Synonyms | (2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide |
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Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby inducing cell differentiation and apoptosis in some tumor cell types.
The listed CAS number is 65646-68-6.
The listed molecular formula is C26H33NO2.
The listed molecular weight is 391.50 g/mol.
(2E,4E,6E,8E)-N-(4-hydroxyphenyl)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide.
The source lists Fenretinidum and Fenretinimide.