Ethyl alpha-oxobenzenebutanoate

Ethyl alpha-oxobenzenebutanoate (also known as ethyl 2-oxo-4-phenylbutanoate or OPBE) is a key intermediate employed to synthesize several angiotensin-converting enzyme (ACE) inhibitor active pharmaceutical ingredients (APIs), particularly the “pril” drugs used to treat hypertension and heart failure.

API Name Enalapril
CAS No 64920-29-2
Molecular Formula C12H14O3
Molecular Weight 206.24 g/mol
Synonyms ethyl 2-oxo-4-phenylbutanoate

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