Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate

It serves as a building block for more complex pyrrole compounds with therapeutic potential, acting as a key precursor in drug discovery. Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate is used mainly as a crucial intermediate in the synthesis of the drug Vonoprazan (TAK-438), a potassium-competitive acid blocker (P-CAB) used for treating acid-related stomach disorders like ulcers, making it vital in pharmaceutical research and manufacturing for this specific class of medications.

API Name Vonoprazan fumarate
CAS No 881674-06-2
Molecular Formula C13H12FNO2
Molecular Weight 233.24 g/mol
Synonyms ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate