Ethyl (2,6-dimethylphenyl)glycinate

Its role in the synthesis is to provide the N-(2,6-dimethylphenyl)glycinate backbone of the molecule, which is later modified and incorporated into the final structure, typically through an acylation step or as a component in a Ugi four-component reaction (Ugi-4CR). Ethyl (2,6-dimethylphenyl)glycinate is a key intermediate in the synthesis of Amenamevir (also known as ASP2151), a potent helicase-primase inhibitor used to treat herpes zoster.

API Name Amenamevir
CAS No 2371-25-7
Molecular Formula C12H17NO2
Molecular Weight 207.27 g/mol
Synonyms ethyl 2-(2,6-dimethylanilino)acetate

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