Estrogens, conjugated

Conjugated Estrogens can cause cancer according to California Labor Code. It can cause developmental toxicity according to state or federal government labeling requirements. The conjugated estrogens are noncrystalline mixtures of purified female sex hormones obtained either by its isolation from the urine of pregnant mares or by synthetic generation from vegetal material. Both of these products are later conjugated to natrium sulfate by ester bonds to make them more water soluble. The conjugated estrogen product contains a mix of estrogen from which about 50% is represented by estrone sulfate followed by 25% of equilin sulfate, 15% of 17-alpha-dehydroequilenin sulfate, 3% of equilenin sulfate, 5% of 17-alpha and 17-beta-dihydroequilenin sulfate, 2% of 17-alpha-estradiolsulfate and 3% of 17-beta-estradiolsulfate. It is grouped under the following drug class(es): Estrogens and Steroids. Its therapeutic use is listed as anti-osteoporosis agents. The directory classifies it as a commercial API with a natural source/manufacturing origin. Other names for this substance include Climopax, Sodestrin, Oestro Feminal, Premarin Cream and Premarin. Its PubChem CID is 45357473.

CAS No 12126-59-9
Molecular Formula C18H21NaO5S
Molecular Weight 372.4 g/mol
Synonyms sodium;[(13S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] sulfate

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