Estriol Succinate

Estriol succinate is an estrogen ester and prodrug of the weak natural estrogen, estriol. Primarily used in menopausal hormone therapy, it relieves symptoms like hot flashes and vaginal dryness. It is available globally (e.g., as Synapause) but requires prescriptions from specialized compounding pharmacies in North America. It is grouped under the following drug class(es): Estrogens and Steroids. The directory classifies it as a commercial API with a semi-synthetic source/manufacturing origin. Other names for this substance include Estriolo succinato and Estrioli succinas. Its PubChem CID is 10577.

CAS No 514-68-1
Molecular Formula C26H32O9
Molecular Weight 488.5 g/mol
Synonyms 4-[[(8R,9S,13S,14S,16R,17R)-17-(3-carboxypropanoyloxy)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl]oxy]-4-oxobutanoic acid

Frequently Asked Questions