Esaxerenone (brand name Minnebro) is a non-steroidal mineralocorticoid receptor (MR) blocker used mainly for treating hypertension (high blood pressure) in Japan, showing benefits in essential hypertension, diabetes-related hypertension, and chronic kidney disease (CKD). It works by blocking mineralocorticoid receptors, promoting sodium excretion without potassium loss, and offering organ protection, especially for kidneys and heart, often used with other drugs like SGLT2 inhibitors or CCBs. Its therapeutic use is listed as cardiovascular. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Esaxerenonum and Esaxerenona. Its PubChem CID is 25052023.
Esaxerenone
| CAS No | 1632006-28-0 |
|---|---|
| Molecular Formula | C22H21F3N2O4S |
| Molecular Weight | 466.5 g/mol |
| Synonyms | 1-(2-hydroxyethyl)-4-methyl-N-(4-methylsulfonylphenyl)-5-[2-(trifluoromethyl)phenyl]pyrrole-3-carboxamide |
Zoho Contact Form
"*" indicates required fields
Frequently Asked Questions
Esaxerenone (brand name Minnebro) is a non-steroidal mineralocorticoid receptor (MR) blocker used mainly for treating hypertension (high blood pressure) in Japan, showing benefits in essential hypertension, diabetes-related hypertension, and chronic kidney disease (CKD).
The listed CAS number is 1632006-28-0.
The listed molecular formula is C22H21F3N2O4S.
The listed molecular weight is 466.5 g/mol.
1-(2-hydroxyethyl)-4-methyl-N-(4-methylsulfonylphenyl)-5-[2-(trifluoromethyl)phenyl]pyrrole-3-carboxamide.
The source lists Esaxerenonum and Esaxerenona.