Eribulin is a fully synthetic macrocyclic ketone analogue of marine sponge natural products. Inhibits growth phase of microtubules via tubulin-based antimitotic mechanism, which leads to G2/M cell-cycle block, disruption of mitotic spindles, and, ultimately, apoptotic cell death after prolonged mitotic blockage Among its listed roles, it functions as a antineoplastic agent and a microtubule-destabilising agent. It is grouped under the following drug class(es): Microtubule inhibitors. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include eribulinum and Eribulin free. Its PubChem CID is 11354606.
Eribulin
| CAS No | 253128-41-5 |
|---|---|
| Molecular Formula | C40H59NO11 |
| Molecular Weight | 729.9 g/mol |
| Synonyms | (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one |
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Frequently Asked Questions
Eribulin is a fully synthetic macrocyclic ketone analogue of marine sponge natural products.
The listed CAS number is 253128-41-5.
The listed molecular formula is C40H59NO11.
The listed molecular weight is 729.9 g/mol.
(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one.
The source lists eribulinum and Eribulin free.