Epalrestat is a monocarboxylic acid that is 1,3-thiazolidine that is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group. It is an inhibitor of aldose reductase (which catalyses the conversion of glucose to sorbitol) and is used to treat some diabetic complications, including neuropathy. Among its listed roles, it functions as a EC 1.1.1.21 (aldehyde reductase) inhibitor. It belongs to the class of thiazolidines and a monocarboxylic acid. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Kinedak and Epalrestatum. Its PubChem CID is 1549120.
Epalrestat
| CAS No | 82159-09-09 |
|---|---|
| Molecular Formula | C15H13NO3S2 |
| Molecular Weight | 319.4 g/mol |
| Synonyms | 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid |
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Frequently Asked Questions
Epalrestat is a monocarboxylic acid that is 1,3-thiazolidine that is substituted on the nitrogen by a carboxymethyl group, at positions 2 and 4 by thioxo and oxo groups, respectively, and at position 5 by a 2-methyl-3-phenylprop-2-en-1-ylidene group.
The listed CAS number is 82159-09-09.
The listed molecular formula is C15H13NO3S2.
The listed molecular weight is 319.4 g/mol.
2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid.
The source lists Kinedak and Epalrestatum.