Elacestrant dihydrochloride

Elacestrant Hydrochloride is the hydrochloride salt form of elacestrant, an orally available, selective estrogen receptor degrader (SERD), with antineoplastic activity. Upon oral administration, elacestrant functions as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the proteosomal degradation of the receptor. This prevents ER-mediated signaling and inhibits proliferation of ER-expressing cancer cells. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Orserdu (TN) and Elacestrant dihydrochloride. Its PubChem CID is 67479909.

CAS No 1349723-93-8
Molecular Formula C30H40Cl2N2O2
Molecular Weight 531.6 g/mol
Synonyms (6R)-6-[2-[ethyl-[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydronaphthalen-2-ol;dihydrochloride

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