Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Edotreotide gallium Ga-68 is indicated in localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography. [Dotatate gallium Ga-68] is used for a similar indication. Dotatate gallium Ga-68 has lower tumor uptake but this data is highly variable between patients. Edotreotide gallium Ga-68 was granted FDA approval on 21 August 2019. The directory classifies it as a commercial API with a peptide source/manufacturing origin. Other names for this substance include Netspot and SomaKit TOC. It is also listed for alternate use as: API Intermediate. Its PubChem CID is 71661158.
Edotreotide gallium Ga-68
| CAS No | 2101630-92-4 |
|---|---|
| Molecular Formula | C65H89GaN14O18S2 |
| Molecular Weight | 1486.5 g/mol |
| Synonyms | 2-[4-[2-[[(2R)-1-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-[[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]-7,10-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;gallium-68(3+) |
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Frequently Asked Questions
Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA). Edotreotide gallium Ga-68 is indicated in localizing somatostatin receptor positive neuroendocrine tumors by positron emission tomography.
The listed CAS number is 2101630-92-4.
The listed molecular formula is C65H89GaN14O18S2.
The listed molecular weight is 1486.5 g/mol.
2-[4-[2-[[(2R)-1-[[(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-4-[[(2R,3R)-1,3-dihydroxybutan-2-yl]carbamoyl]-7-[(1R)-1-hydroxyethyl]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]-7,10-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;gallium-68(3+).
The source lists Netspot and SomaKit TOC.