Dolasetron mesylate monohydrate

Dolasetron mesylate monohydrate is a selective serotonin subtype-3 (5-HT₃) receptor antagonist used to prevent chemotherapy-induced and postoperative nausea and vomiting. As the active ingredient in medications like ANZEMET, it blocks serotonin at vagal nerve terminals and the brain’s emetic center to inhibit vomiting reflexes. It is grouped under the following drug class(es): Antiemetics and Serotonin agents. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Anzemet and Dolasetron mesylate anhydrous. Its PubChem CID is 6918119.

CAS No 878143-33-0
Molecular Formula C20H26N2O7S
Molecular Weight 438.50 g/mol
Synonyms methanesulfonic acid;[(3S,7R)-10-oxo-8-azatricyclo[5.3.1.03,8]undecan-5-yl] 1H-indole-3-carboxylate;hydrate

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