Divalproex sodium

Divalproex sodium is a stable coordination compound comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex dissociates to the valproate ion in the gastrointestinal tract. This agent binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. Divalproex may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels. It is grouped under the following drug class(es): Mood stabilizers and Psychotropic agents. Its therapeutic use is listed as anticonvulsants, migraine preventive agents and mood stabilizers. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Sodium hydrogen valproate, Depakote Sprinkles and Epival. Its PubChem CID is 23663956.

CAS No 76584-70-8
Molecular Formula C16H31NaO4
Molecular Weight 310.40 g/mol
Synonyms sodium;2-propylpentanoate;2-propylpentanoic acid

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