Diphenhydramine hydrochloride

Diphenhydramine Hydrochloride is the hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. It is grouped under the following drug class(es): Antiemetics, Hypnotics and Sedatives. Its therapeutic use is listed as dermatologicals. The directory classifies it as a commercial API with a synthetic source/manufacturing origin. Other names for this substance include Allergan, Bendylate, Dibenil and Eldadryl. Its PubChem CID is 8980.