Dextrothyroxine sodium

Dextrothyroxine sodium is a dextrorotary isomer of thyroid hormone mainly used historically as a lipid-lowering agent to treat hyperlipidemia, particularly to reduce elevated serum cholesterol and LDL levels. It acts by increasing hepatic catabolism of LDL and increasing fecal excretion of cholesterol, though its use has been largely superseded due to cardiac safety concerns. It is grouped under the following drug class(es): Cholesterol-reducing agents. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Sodium dextrothyroxine and Dextrothyroxinum natricum. Its PubChem CID is 23690433.

CAS No 137-53-1
Molecular Formula C15H10I4NNaO4
Molecular Weight 798.85 g/mol
Synonyms sodium (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate

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