Dextrothyroxine sodium is a dextrorotary isomer of thyroid hormone mainly used historically as a lipid-lowering agent to treat hyperlipidemia, particularly to reduce elevated serum cholesterol and LDL levels. It acts by increasing hepatic catabolism of LDL and increasing fecal excretion of cholesterol, though its use has been largely superseded due to cardiac safety concerns. It is grouped under the following drug class(es): Cholesterol-reducing agents. The directory classifies it as a discontinued API with a synthetic source/manufacturing origin. Other names for this substance include Sodium dextrothyroxine and Dextrothyroxinum natricum. Its PubChem CID is 23690433.
Dextrothyroxine sodium
| CAS No | 137-53-1 |
|---|---|
| Molecular Formula | C15H10I4NNaO4 |
| Molecular Weight | 798.85 g/mol |
| Synonyms | sodium (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate |
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Dextrothyroxine sodium is a dextrorotary isomer of thyroid hormone mainly used historically as a lipid-lowering agent to treat hyperlipidemia, particularly to reduce elevated serum cholesterol and LDL levels.
The listed CAS number is 137-53-1.
The listed molecular formula is C15H10I4NNaO4.
The listed molecular weight is 798.85 g/mol.
sodium (2R)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate.
The source lists Sodium dextrothyroxine and Dextrothyroxinum natricum.